biotechnology research center
Main Activities

Effects of natural agents with plant origin on human cancer cell lines

Effects of natural agents with plant origin on human cancer cell lines

Other Activities

• Eval uati on, translati on, and valida ti on of sta ndardized pati ent-rep ort ed questi onnaires • Pati ent follow-up • Nuclear medicine depar tment, genetic lab, and collaborati on with st em cell depa rtment a nd conferences

  • Cancer Treatment with targeted nanoparticles
  • Formulation of protein and peptide drug delivery systems
  • Analysis of drugs and herbal substances, such as saffron
  • Drug resistance mechanisms in cancer
  • Biofilms and the effects of drugs on them

Human being is always exploring the unknown and making great efforts to get better understanding of the surrounding world. The invention of an instrument, a method, a treatment, a drug, or any other novel things pushes the human being towards evolution and completion, especially if these inventions are conducted in the field of medical sciences and their reciprocal effects are accompanied by modern technology. This will lead to the development of technologies, utilization of live beings to make or manipulate products, promotion of plant or animal quality, and alteration of microorganism characteristics for special applications.

Bu Ali Research Institute formally commenced its activities more than a decade ago with the purpose of education and research in the field of biotechnology, especially in domains related to pharmacy and medicine. The scope of research in this institute ranges from investigating the effects of natural agents with plant offspring on human tumor cell to using spotted nanoparticles, and biofilms, as well as examining the effects of drugs. With an emphasis on the treatment of special diseases, this center has considered making efforts in finding drug resistance mechanisms for cancer, analysis of drugs, effective herbaceous materials, and formula of peptide and protein drugs. Ultimately, it should be noted that this center trains Ph.D. students with the purpose of educating experts and experienced individuals in order to take another vital step for the development of medical sciences.

National Academic Article

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Internationl Academic Articles

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Research Programers

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National Academic Article

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Educational Activities

Training Ph.D. students in specialized courses

Research/Scientific Achievenments

Producing Sinadoxosome anti-cancer nanodrug

Winning 4 awards in Raazi Festival

Professional/Exclusive Activities
Research Activities
National / International Rating

Top University Research Center in 2014

EXECUTED RESEARCH PROGRAMS
Center quantum dots and their application in supplying targeted nanoprobes connected to the Alpameter using polymer zoom systems in order to take images of glioblastoma cells
Immunization of BLAB/C mice against leishmaniosis using cationic DDAB nanoliposomes
containing parasitic antigens for leishmanial and adjuvant TDB
Investigation of the role of Akt in MCF-7 breast adenocarcinoma cell responses and derivative resistant to that of tumor necrosis factor-alpha
Investigation of the expression of gangrene in different cell lines resistant to anticancer drugs and comparing it with the expression of oncoprotein in drug-resistant parental cell lines
EXECUTING RESEARCH PROGRAMS
Identifying disturbed gene expression networks in human leukemia stem cells and investigating of their correlation with micro expression pattern for RNAs
Synthesis and investigation of cationic surfactant activity based on functional peptide sequence as nanocarriers for gene delivery
Investigation of cell adhesion molecules in patients suffering from solid tumors after treatment using curcumin phospholipid complex
Proteomics-based evaluation of the difference in protein expression levels of HepG2 cell lines by proximity using Safmarine